Medical disclaimer: GutVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you are pregnant, take medicines, or have a medical condition. New, severe or worsening symptoms (such as blood in the stool, weight loss, fever, or night-time symptoms) need a doctor, not a supplement. Full disclaimer.

Saccharomyces boulardii vs L. rhamnosus GG (Culturelle)

On Reddit, owners rate Saccharomyces boulardii higher overall (4.0 vs 3.9). Scores summarize self-reported experiences and are not evidence that either will work for you.

Saccharomyces boulardiiL. rhamnosus GG (Culturelle)
Typecapsulescapsules
GutVerdict score4.03.9
Owner sentiment3.64.1
Recommendations3.71.9
Tolerability4.84.8
Owner comments47853
Rated comments17719
Unwanted effects reported8%5%
Top praiseDose & timing, Urgency & loose stoolsCost, Dose & timing
Top complaintsSide effects, Urgency & loose stoolsSide effects

By symptom

ContextSaccharomyces boulardiiL. rhamnosus GG (Culturelle)
IBS-C & constipation16 of 21 positive4 of 4 positive
IBS-D & loose stools28 of 32 positiveToo few comments
Bloating & gas24 of 26 positiveToo few comments
SIBO65 of 87 positive7 of 7 positive
After antibiotics39 of 43 positive4 of 4 positive
Pain & cramping13 of 16 positiveToo few comments

What owners say about Saccharomyces boulardii

4/5 Cost

“I've tolerated taking Florastor 3x a day during antibiotics.”

owner comment via r/SIBO · 2026-10-04 · 6 upvotes
1/5

“Boulardii followed by a month of daily lentils solved 3 years of gut imbalance for me.”

owner comment via r/Microbiome · 2026-09-28 · 12 upvotes
4/5

“Just added S Boulardii, which I previously tried and reacted to but now doing much better on it.”

owner comment via r/SIBO · 2026-05-15 · 10 upvotes

Full Saccharomyces boulardii page →

What owners say about L. rhamnosus GG (Culturelle)

4/5

“One one of probiotics I was taking, LGG get rid of bilophila, but increased desulfovibrio.”

owner comment via r/Microbiome · 2026-04-27 · 4 upvotes
4/5

“I have had a lot of great results taking phages with s boulardi (opposes bad bacteria in small intestine) and bifido longum (bb536) with L rhamnosus.”

owner comment via r/Microbiome · 2026-06-29 · 3 upvotes
4/5

“I started taking Culturelle Digestive Daily Probiotic twice daily to repair my gut.”

owner comment via r/IBS · 2025-12-30 · 2 upvotes

Full L. rhamnosus GG (Culturelle) page →

Talk to a doctor or pharmacist before switching or combining supplements, particularly if you take other medicines.