Medical disclaimer: GutVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you are pregnant, take medicines, or have a medical condition. New, severe or worsening symptoms (such as blood in the stool, weight loss, fever, or night-time symptoms) need a doctor, not a supplement. Full disclaimer.
Probiotics · capsules

L. rhamnosus GG (Culturelle): What People With IBS Report on Reddit

L. rhamnosus GG (Culturelle) illustration

Illustration, not a product photo.

Lacticaseibacillus rhamnosus GG, one of the most studied single probiotic strains.

3.9 GutVerdict score

53 owner comments (19 with a clear rating) from r/IBS, r/Microbiome, r/SIBO, November 2025 to October 2026. Top 28% of the 36 rated supplements.

Owner sentiment4.1
Recommendations1.9
Tolerability4.8
ValueNot rated

Value is not rated: the example products differ too much in dose to compare cost fairly. How we score.

The short version

L. rhamnosus GG (Culturelle) is rated about average among the supplements we track: 3.9/5. Of 19 rated owner comments, 18 were positive, 1 mixed and 0 negative; 1 mention an unwanted effect. People talk most about cost and side effects.

Reddit comments are self-reported and unverified. They tell you what people noticed, not whether a supplement works or is safe for you.

What it is

Safety and interactions

Supplements can interact with medicines. Talk to a doctor or pharmacist first, especially if you are pregnant, take prescription medicine, or have red-flag symptoms. See supplement safety and interactions.

Reports by symptom

ContextRated owner commentsPositiveNegativeUnwanted effects
SIBO7701
IBS-C & constipation4401
After antibiotics4400

What Reddit owners say

Commonly praised

  • Cost: 2 owner comments

Common complaints

  • Side effects: 1 owner comment
4/5

“One one of probiotics I was taking, LGG get rid of bilophila, but increased desulfovibrio.”

owner comment via r/Microbiome · 2026-04-27 · 4 upvotes
4/5

“I have had a lot of great results taking phages with s boulardi (opposes bad bacteria in small intestine) and bifido longum (bb536) with L rhamnosus.”

owner comment via r/Microbiome · 2026-06-29 · 3 upvotes
4/5

“I started taking Culturelle Digestive Daily Probiotic twice daily to repair my gut.”

owner comment via r/IBS · 2025-12-30 · 2 upvotes
+14 more owner comments
4/5

“It's called Culturelle. I think there is some dairy, but I was really desperate and saw it recommended by gastros so I decided to try it.”

owner comment via r/IBS · 2026-03-29 · 2 upvotes
5/5

“I then introduced Lactobacillus rhamnosus GG and I feel so much better.”

owner comment via r/Microbiome · 2026-03-13 · 2 upvotes
4/5

“Back when my doc prescribed L.Rhamnosus it worked like wonders, thought I was recovering.”

owner comment via r/SIBO · 2026-09-15 · 2 upvotes
5/5

“Boulardi, culturelle, occasional Visbiome) that worked wonders for me and started having two poops on a perfect schedule nearly every day (I'm still on the probiotic regimen, and it is helping restore things slowly again).”

owner comment via r/IBS · 2026-02-24 · 1 upvotes
4/5

“I've been using Culturelle the last 4 years as they were recommended by my gastro when I was having my original issues and they initially worked great.”

owner comment via r/IBS · 2026-03-13 · 1 upvotes
4/5 Cost

“I switched from Culturelle to Florastor last week - I don't like how expensive it is for how little pills they put in the box, but I'm hoping its more effective!”

owner comment via r/IBS · 2026-05-29 · 1 upvotes
3/5

“I used Florastor to clear out the bad gut bacteria, dropped Culturelle (did nothing for me), and used Align to repopulate the good stuff.”

owner comment via r/IBS · 2026-09-03 · 1 upvotes
4/5 CostSide effects

“The Culturelle brand (I was taking) is cheap and widely available.”

owner comment via r/Microbiome · 2025-11-10 · 1 upvotes
5/5

“Rhamnosus GG it is like miracle, It works for me.”

owner comment via r/Microbiome · 2025-11-30 · 1 upvotes
4/5

“Luckily enough, once my original product has been discontinued (it was from Culturelle IIRC), SuperHMO became available in the EU.”

owner comment via r/Microbiome · 2026-06-01 · 1 upvotes
4/5

“I’ve had success using URO brand probiotics and then read about lactobacillus rhamnosus GG and have incorporated that as well.”

owner comment via r/Microbiome · 2026-06-30 · 1 upvotes
4/5

“Based on this post from MastAttack, I started with Culturelle probiotics.”

owner comment via r/Microbiome · 2026-08-04 · 1 upvotes
4/5

“Culturelle worked great for me”

owner comment via r/Microbiome · 2026-08-23 · 1 upvotes
4/5

“I have bilophila and very low dose adp ( I break the pills) and Rhamnosus GG are helping me.”

owner comment via r/SIBO · 2026-03-13 · 1 upvotes

Brands with their own owner reviews

Example products

These are examples of L. rhamnosus GG (Culturelle) products sold on Amazon. They are not ranked by Reddit and the score above is for the ingredient, not a specific product. Check the label for dose and other ingredients.

Example product · not Reddit-scored

Culturelle Digestive Daily Probiotic for Men & Women, 10B CFUs, 30 Count

Brand on Reddit: 3.8 from 30 owner comments · Culturelle owner reviews
$17.47 on Amazon (price as of 2026-11-03). Prices change; check Amazon for the current price.
Example product · not Reddit-scored

Culturelle Ultimate Strength Probiotic For Women & Men, 20B CFUs, 30 Count

Brand on Reddit: 3.8 from 30 owner comments · Culturelle owner reviews
$27.47 on Amazon (price as of 2026-11-03). Prices change; check Amazon for the current price.

Research to read

Published studies (we list them so you can read the evidence yourself; inclusion is not an endorsement):

FAQ

What do people with IBS say about L. rhamnosus GG (Culturelle) on Reddit?

Across 53 Reddit comments from people who say they have used it, 18 of 19 rated comments were positive and 0 negative, for a GutVerdict score of 3.9/5. These are self-reported experiences, not clinical evidence.

Do people report side effects with L. rhamnosus GG (Culturelle)?

1 of 19 rated owner comments (5%) describe an unwanted effect such as gas, bloating or an upset stomach. Check the safety notes on this page and ask a doctor or pharmacist before starting.

Who talks about L. rhamnosus GG (Culturelle) most?

Most rated owner comments come from people in r/SIBO and others who mention SIBO (7 comments, 7 positive).

Is L. rhamnosus GG (Culturelle) scored on clinical evidence?

No. The score summarizes Reddit owner comments only. Factual statements on this page link to NIH or PubMed sources, and nothing here is medical advice.

Related supplements

Comparisons: Saccharomyces boulardii vs L. rhamnosus GG (Culturelle)

Last updated 2026-11-03. Mentions scanned: 276 in 220 threads.