Medical disclaimer: GutVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you are pregnant, take medicines, or have a medical condition. New, severe or worsening symptoms (such as blood in the stool, weight loss, fever, or night-time symptoms) need a doctor, not a supplement. Full disclaimer.

Gut Supplements Rated by Reddit Owners

36 supplement ingredients and types, scored from 9,413 comments by people who say they have used them (November 2025 to October 2026). Scores summarize self-reported experiences in r/IBS, r/SIBO, r/Constipation, r/Microbiome and r/Supplements; they are not clinical evidence. How we score.

Digestive enzymes illustration
Digestive enzymes

Digestive enzymes

4.3 (809 owner comments)
Bloating & gasPain & cramping

“I began to take 1 capsule before each meal together with digestive enzymes and my symptoms lessened by about 70-80% in a few weeks.”

What owners report →
Psyllium husk illustration
Fiber

Psyllium husk

4.2 (1064 owner comments)
RegularityStool form

“Neither psyllium nor anything else should be a sole source of fiber for anyone.”

What owners report →
Magnesium citrate illustration
Magnesium

Magnesium citrate

4.0 (843 owner comments)
RegularityPain & cramping

“Today I would take some magnesium citrate, because wherever is fermenting in your gut needs to be released not stuck up inside of you.”

What owners report →
L-glutamine illustration
Gut-lining & amino acids

L-glutamine

4.0 (456 owner comments)
Bloating & gasSide effects

“My condition improved when I started to take Glutamine in the morning and one banana before bed.”

What owners report →
Magnesium oxide illustration
Magnesium

Magnesium oxide

4.0 (279 owner comments)
RegularityBloating & gas

“Now at 32 I have not had an attack like this in almost a year whilst taking 400mg of magnesium oxide every night before bed..”

What owners report →
Iberogast (STW 5) illustration
Herbal & oils

Iberogast (STW 5)

3.8 (124 owner comments)
Bloating & gasPain & cramping

“I can not tolerate iberogast but I do take and tolerate Atantril which I highly recommend for IMO, has, bloat and brain fog.”

What owners report →
Oregano oil illustration
Herbal antimicrobials

Oregano oil

3.8 (494 owner comments)
Bloating & gasSide effects

“- solved the bloating with berberine and oil of oregano”

What owners report →
Acacia fiber illustration
Fiber

Acacia fiber

3.8 (106 owner comments)
GentleRegularity

“Acacia is the other gentle one worth knowing about, it ferments so slowly that even sensitive guts handle it well and it actually feeds Bifidobacterium selectively.”

What owners report →
Atrantil illustration
Herbal & oils

Atrantil

3.8 (181 owner comments)
Bloating & gasSide effects

“I have heard that some folks in similar situations find a lot of relief by using Atrantil.”

What owners report →
Lactase enzyme illustration
Digestive enzymes

Lactase enzyme

3.7 (79 owner comments)
Stopped workingPain & cramping

“I didn't think I was lactose intolerant but tried lactase tablets after 40 years if IBS-C.”

What owners report →
DGL licorice illustration
Gut-lining & amino acids

DGL licorice

3.7 (77 owner comments)
Side effectsBloating & gas

“Those were a game changer that pure one with the DGL plus that one took the pain away but you gotta eat right basically plain it sucks.”

What owners report →
Seed DS-01 illustration
Probiotics

Seed DS-01

3.7 (45 owner comments)
Bloating & gasSide effects

“Seed probiotics (I can’t take too many days otherwise I get constipated).”

What owners report →
Activated charcoal illustration
Other supplements

Activated charcoal

3.7 (106 owner comments)
Bloating & gasPain & cramping

“Hot coffee helps get things moving, especially if I drink a glass of water with activated charcoal beforehand.”

What owners report →
Magnesium glycinate illustration
Magnesium

Magnesium glycinate

3.7 (264 owner comments)
RegularitySide effects

“Manage stress (I take L theanine and magnesium glycinate and it’s helped me to have a calmer response)”

What owners report →
Slippery elm illustration
Gut-lining & amino acids

Slippery elm

3.7 (81 owner comments)
Urgency & loose stoolsBloating & gas

“Slippery elm helped a little too if you haven’t tried that but it didn’t as much for me.”

What owners report →
Allicin (Allimed / Allimax) illustration
Herbal antimicrobials

Allicin (Allimed / Allimax)

3.6 (425 owner comments)
Side effectsBloating & gas

“The allicin compound is where the magic happens, but you gotta crush or chop it and let it sit for like 10 minutes before cooking to activate it properly.”

What owners report →
Berberine illustration
Herbal antimicrobials

Berberine

3.6 (569 owner comments)
Side effectsBloating & gas

“My psychiatrist/medicine manager actually recommended I try berberine, which is a plant based supplement derived from traditional chinese medicine.”

What owners report →
Bovine colostrum illustration
Gut-lining & amino acids

Bovine colostrum

3.6 (80 owner comments)
Bloating & gasSide effects

“Organ meats, like pancreas, gallbladder, and also colostrum are so amazing for gut health.”

What owners report →
Candibactin-AR / BR illustration
Herbal antimicrobials

Candibactin-AR / BR

3.5 (121 owner comments)
Side effectsCost

“I went to a doctor that told me to take allicin and candibactin-br for months and it helped rebalance my gut.”

What owners report →
Marshmallow root illustration
Gut-lining & amino acids

Marshmallow root

3.5 (21 owner comments)
CostRegularity

“I take 10 to 15 grams of creatine mixed with marshmallow root extract powder (to reduce cramps) + some electrolytes, all in water.”

What owners report →
L. reuteri illustration
Probiotics

L. reuteri

3.5 (278 owner comments)
Bloating & gasSide effects

“I used that when I first started making Reuteri yogurt now I am using Oxiceutics which a lot of people suspect is the BioGaia strains just not named.”

What owners report →
Akkermansia (Pendulum) illustration
Probiotics

Akkermansia (Pendulum)

3.3 (124 owner comments)
Bloating & gasSide effects

“Akkermansia is primarily a microbe implicated in its interactions with the mucosal layer, because it helps to maintain the turnover of the mucosa by metabolizing the mucosa.”

What owners report →