Gut-lining & amino acids
L-glutamine
4.0 (456 owner comments)
Bloating & gasSide effects
“My condition improved when I started to take Glutamine in the morning and one banana before bed.”
What owners report →Medical disclaimer: GutVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you are pregnant, take medicines, or have a medical condition. New, severe or worsening symptoms (such as blood in the stool, weight loss, fever, or night-time symptoms) need a doctor, not a supplement. Full disclaimer.
Gut-lining & amino acids · chewable tablets
DGL licorice: What People With IBS Report on Reddit
Illustration, not a product photo.
Licorice with most glycyrrhizin removed (deglycyrrhizinated).
3.7 GutVerdict score
77 owner comments (26 with a clear rating) from r/SIBO, r/Microbiome, r/IBS, r/Constipation, November 2025 to October 2026. Top 59% of the 36 rated supplements.
Owner sentiment3.9
Recommendations1.9
Tolerability4.5
ValueNot rated
Value is not rated: the example products differ too much in dose to compare cost fairly. How we score.
The short version
DGL licorice is rated about average among the supplements we track: 3.7/5. Of 26 rated owner comments, 23 were positive, 1 mixed and 2 negative; 4 mention an unwanted effect. People talk most about side effects and bloating & gas.
Reddit comments are self-reported and unverified. They tell you what people noticed, not whether a supplement works or is safe for you.
There is a separate ranking of what people with IBS-D rate highest. People also compare supplements for SIBO on Reddit. Reddit owners also rank supplements by bloating reports.
What it is
- DGL is licorice with most glycyrrhizin removed; glycyrrhizin is the part linked to serious side effects.[NCCIH]
Safety and interactions
- Regular licorice root (not DGL) can raise blood pressure and cause heart rhythm problems; check the label says deglycyrrhizinated.[NCCIH]
Supplements can interact with medicines. Talk to a doctor or pharmacist first, especially if you are pregnant, take prescription medicine, or have red-flag symptoms. See supplement safety and interactions.
Reports by symptom
| Context | Rated owner comments | Positive | Negative | Unwanted effects |
|---|---|---|---|---|
| SIBO | 14 | 13 | 0 | 2 |
| Bloating & gas | 4 | 4 | 0 | 1 |
| IBS-D & loose stools | 3 | 3 | 0 | 0 |
| After antibiotics | 3 | 3 | 0 | 0 |
What Reddit owners say
Commonly praised
- Bloating & gas: 2 owner comments
- Urgency & loose stools: 1 owner comment
- Cost: 1 owner comment
Common complaints
- Side effects: 4 owner comments
4/5“It likely went on to further damage the cells of the stomach and lower acid production even if you are no longer infected and obviously i can't guarantee that without testing but taking betaine hcl as a mock stomach acid, DGL and…”
5/5 Bloating & gasCost“Those were a game changer that pure one with the DGL plus that one took the pain away but you gotta eat right basically plain it sucks.”
4/5 Bloating & gas“Standard process pmg that is natural food for the body .i took the brand is in the picture on my page DGL Plus , GI supplement has probiotic in it and other stuff that helps the gut and the stomach from the gas the bloating all that you…”
+14 more owner comments
4/5“Degyclinnorized licorice (DGL) helped me with my low stomach acid immensely.”
4/5 Urgency & loose stools“Something with ginger/artichoke leak extract/DGL may be helpful with the stomach stuff (mega guard by microbiome labs as an example, and mega IgG 2000 from them is what helps me with die off reaction symptoms like constipation or diarrhea).”
4/5“Then a week later I started DGL (read the ingredient lists on the bottle, bcs it can still have some extra ingredients that can trigger the inflammation).”
4/5“I would also recommend zinc-carnosin and DGL - these two worked for me better than anything else.”
4/5“I was taking zinc-carnisin and DGL. It helped.”
4/5“I ended up using DGL and helped. I recently had an endoscopy and they saw inactive chronic gastritis on the tissue level so it did calm but there was evidence it had been there.”
4/5“I take dgl and sunfiber. This is going to sound insane, but one of the things that I think really helped me was elderberry gummies.”
4/5“When wedge/pepcid/ppis weren’t working for me, I added melatonin and Deglycyrrhizinated Licorice supplements ~30 minutes before bedtime and saw improvement.”
4/5“I take DGL licorice chewables before meals, it helps.”
4/5“I take two DGL licorice pills (500 mg) while I'm cooking (15-20 minutes before I eat) and 3-4 ginger pills right before.”
4/5“For gastritis Instead i am taking zinc l-Carnosine and DGL/slippery elm supplements together that seem to work better and has a better scientific backing to repair the stomach.”
4/5“When my problem was acute, what helped me the most is DGL.”
4/5“For dysbiiosis I recommend you start all of these: glutamine, DGL licorice, clove extract, betaine HCL + pepsin to start.”
4/5“I can’t remember as I was taking Slippery Elm and DGL before then which helped 70%.”
Example products
These are examples of DGL licorice products sold on Amazon. They are not ranked by Reddit and the score above is for the ingredient, not a specific product. Check the label for dose and other ingredients.
Example product · not Reddit-scored
Natural Factors DGL Chewable, Licorice Root Extract, 180 Tablets
$22.37 on Amazon (price as of 2026-11-03). Prices change; check Amazon for the current price.
Example product · not Reddit-scored
Nature's Way Extra Strength (1) DGL Ultra, DGL Chewable Tablets for Digestive Support*, Deglycyrrhizinated Licorice GutGard Extract
$18.49 on Amazon (price as of 2026-11-03). Prices change; check Amazon for the current price.
Research to read
Published studies (we list them so you can read the evidence yourself; inclusion is not an endorsement):
FAQ
What do people with IBS say about DGL licorice on Reddit?
Across 77 Reddit comments from people who say they have used it, 23 of 26 rated comments were positive and 2 negative, for a GutVerdict score of 3.7/5. These are self-reported experiences, not clinical evidence.
Do people report side effects with DGL licorice?
4 of 26 rated owner comments (15%) describe an unwanted effect such as gas, bloating or an upset stomach. Check the safety notes on this page and ask a doctor or pharmacist before starting.
Who talks about DGL licorice most?
Most rated owner comments come from people in r/SIBO and others who mention SIBO (14 comments, 13 positive).
Is DGL licorice scored on clinical evidence?
No. The score summarizes Reddit owner comments only. Factual statements on this page link to NIH or PubMed sources, and nothing here is medical advice.
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What owners report →Last updated 2026-11-03. Mentions scanned: 316 in 216 threads.